国际眼科纵览

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角结膜肿瘤的诊断及治疗

黄晶晶  梁庆丰  李彬   

  1. 100005 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室
  • 收稿日期:2015-08-17 出版日期:2015-12-22 发布日期:2015-12-22
  • 通讯作者: 李彬,Email:libin43_99@163.com
  • 基金资助:

    国家自然科学基金(81172393)

The diagnosis and treatment of keratoconjunctival tumors

HUANG Jing-jing, LIANG Qing-feng, LI Bin   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Centre,  Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China
  • Received:2015-08-17 Online:2015-12-22 Published:2015-12-22
  • Contact: LI Bin, Email: libin43_99@163.com

摘要:

角结膜肿瘤中绝大部分为结膜肿瘤,原发于角膜的肿瘤非常少见。其中,良性肿瘤以色素痣、皮样瘤、皮脂瘤常见,恶性肿瘤以鳞状细胞癌、黑色素瘤、淋巴瘤相对多见。组织病理学为肿瘤诊断的“金标准”。随着活体共聚焦显微镜的发展和应用,可为病变性质的确定提供一定的参考价值。对于无症状的良性肿瘤,一般建议观察,定期复查。若观察过程中,发现瘤体出现恶变倾向,需尽早手术切除并行组织病理学检查。对恶性肿瘤,最常用的治疗方式为局部扩大切除加结膜边缘冷冻治疗。有时也会结合放疗、化疗,甚至眼球摘除或眼内容物剜除以挽救患者生命。(国际眼科纵览, 2015,  39:   394-400)

Abstract:

Conjunctival tumors account for vast majority of keratoconjunctival tumors. The primary cornea  tumors are very rare. Common benign tumors are dermoid, melanocytic nevi, and dermolipoma. Common malignant tumors are squamous cell carcinoma, melanoma, and lymphoma. Histopathology examination is the "gold standard" for tumor diagnosis. In recent years, with the development and applications of in vivo confocal microscopy, it  can also provide a reference value for determining the nature of the lesion. Observation is a common  choice for  management of most benign, asymptomatic tumors. If  a  malignant transition tendency is observed, both surgery and histopathological examinations are needed as soon as possible. For clinical suspected malignant tummors, the most common treatment is local extended resection and cryotherapy. Sometimes, it may need to be combined with radiotherapy, chemotherapy, or even enucleation or evisceration to save the patient's life.   (Int Rev Ophthalmol,  2015,  39:     394-400)